millipore,
密理博,HSCRMAG32KPX14,MILLIPLEX MAP Human Soluble Cytokine Receptor Panel, HSCRMAG-32K- Immunology Multiplex Assay
重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
|---|
| sCD30, sEGFR, sgp130, sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII, sVEGF-R1, sVEGF-R2, sVEGF-R3
| H
| Mplex
| Luminex xMAP
|
| Description
|
| Catalogue Number | HSCRMAG32KPX14 |
| Trade Name |
|
| Description | MILLIPLEX MAP Human Soluble Cytokine Receptor Panel, HSCRMAG-32K- Immunology Multiplex Assay |
| Background Information | Cytokine receptors constitute an integral part of cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane- bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists. |
| Product Information
|
| Detection method | Luminex xMAP |
| Configuration | Premixed |
| Precision, % |
- Inter-assay: <15%
- Intra-assay: <10%
|
| Panel Type | MAGNETIC Cytokines/Chemokines |
| Quality Level | MQ200
|
| Applications
|
| Application | Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples. |
| Key Applications |
|
| Application Notes | • This is an overnight incubation assay with a 1-hour incubation with detection antibodies requiring 25 µL of a 1:5 dilution for plasma or serum, or 25 μL cell culture supernatant per well.
• This kit may be used for the analysis of all or any combination of the Human Soluble Cytokine Receptor panel analytes in serum, plasma or tissue/cell lysate and culture supernatant. |
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
- sCD30
- sEGFR
- sgp130
- sIL-1RI
- sIL-1RII
- sIL-2Rα
- sIL-4R
- sIL-6R
- sRAGE
- sTNFRI
- sTNFRII
- sVEGF-R1
- sVEGF-R2
- sVEGF-R3
|
| Cross Reactivity | There is no detectable cross-reactivity within the panel. |
| Accuracy |
|
| Physicochemical Information
|
| Sensitivity |
- 4 - 208 pg /mL (Overnight Incubation minDC)
- Please see kit protocol for individual assay sensitivities.
|
| Linearity of Dilution | |
| Standard Curve Range |
- sCD30, sgp130, sIL-1RI, sIL-2Rα: 24.4 – 100,000 pg/mL
- sEGFR, sIL-1RII, sVEGF-R1, sVEGF-R2, sVEGF-R3:122.1 – 500,000 pg/mL
- sIL-4R, sIL-6R, sRAGE, sTNFRI, sTNFRII: 12.2 - 50,000 pg/mL
|
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Storage and Shipping Information
|
| Storage Conditions | Recommended storage for kit components is 2 - 8°C. |
| Packaging Information
|
| Material Size | 96-well plate |
