millipore,
密理博,RBN1MAG-31K,MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 - Bone Metabolism Multiplex Assay
重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
|---|
| ACTH, DKK-1, FGF-23, Insulin, Leptin, Osteoprotegerin, PTH, SOST
| R
| Mplex
| Luminex xMAP
|
| Description
|
| Catalogue Number | RBN1MAG-31K |
| Trade Name |
|
| Description | MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 - Bone Metabolism Multiplex Assay |
| Background Information | EMD millipore recognizes the need to better understand the role that bone metabolism biomarkers play in preserving normal bone structure and in the development of disease. Bone metabolism is the dynamic process of ongoing bone deposition and resorption, controlled by osteoblasts, osteocytes, and osteoclasts. While osteoblasts and osteocytes (osteoblasts surrounded by matrix) are responsible for bone deposition, osteoclasts are responsible for bone resorption. Both are required to maintain bone structure, as well as an adequate supply of calcium. To maintain this metabolic balance these cells rely on complex signaling pathways involving hormones and cytokines to achieve the appropriate rates of growth and differentiation. |
| Product Information
|
| Detection method | Luminex xMAP |
| Configuration | Design your multiplex kit by choosing available analytes within this panel. |
| Precision, % |
- Intra-assay: <10
- Inter-assay: <15
|
| Panel Type | MAGNETIC Bone |
| Quality Level | MQ200
|
| Applications
|
| Application | This MILLIPLEX MAP Rat Bone Magnetic Bead Panel 1 is a Bone Metabolism multiplex assay. The analytes available for this multiplex kit are: ACTH, Insulin, Leptin, Osteoprotegerin, DKK-1, SOST, FGF-23, PTH. |
| Key Applications |
|
| Application Notes | • No cross reactivity between the antibodies for an analyte in these panels were observed. All assays can be ran as a same day or overnight incubation assay.
• The Rat Bone Panel 1 (RBN1MAG-31K) is designed for measurement of serum or plasma samples and can be assayed as a same day or overnight incubation assay. |
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
- ACTH
- DKK-1
- FGF-23
- Insulin
- Leptin
- Osteoprotegerin
- PTH
- SOST
|
| Cross Reactivity | The antibody pairs in each panel do not show cross reactivity to the other analytes within the panel |
| Accuracy |
|
| Physicochemical Information
|
| Sensitivity |
|
| Linearity of Dilution | |
| Standard Curve Range |
- ACTH and OPG: 10-40,000 pg/mL
- DKK-1: 12-50,000 pg/mL
- Insulin: 31-125,000 pg/mL
- Leptin: 7-30,000 pg/mL
- SOST: 5-20,000 pg/mL
- FGF-23: 22-90,000 pg/mL
- PTH: 0.4-1,500 pg/mL
|
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Packaging Information
|
| Material Size | 96-well plate |
