millipore,
密理博,HCCBP3MAG-58K,MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay
重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
|---|
| Cathepsin D, Galectin-3, Ferritin, Fibroblast Activation Protein, IGFBP-3, Melanoma Inhibitory Activation Protein, Myeloperoxidase, Sex Hormone Binding Globulin
| H
| Mplex
| Luminex xMAP
|
| Description
|
| Catalogue Number | HCCBP3MAG-58K |
| Trade Name |
|
| Description | MILLIPLEX MAP Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay |
| Overview | MILLIPLEX MAP Circulating Cancer Biomarker Magnetic Bead Panel 3 consists of 8 circulating cancer biomarkers that can be used to study a wide range of tumor types. |
| Background Information | Cancer research has always focused on intracellular biomarkers, such as HER2 and B-Raf, and in recent years, more and more attention has shifted to include extracellular cancer biomarkers. While the use of intracellular markers in research helps clarify the process of oncogenesis, circulating cancer biomarkers give insight into how the body responds to the presence of a tumor, the dysregulation of homeostasis and the relationship between a tumor and its environment. Study of isolated biomarkers, whether intracellular or circulating, is often inadequate to fully characterize the complex relationship between tumor and non-tumor. Consequently, multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology. |
| Product Information
|
| Detection method | Luminex xMAP |
| Configuration | Design your multiplex kit by choosing available analytes within this panel. |
| Precision, % |
- Intra Assay: 5 - 8
- Inter Assay: 5 - 17
|
| Panel Type | MAGNETIC Circulating Cancer |
| Quality Level | MQ200
|
| Applications
|
| Application | Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples. |
| Key Applications |
|
| Application Notes | • This is an overnight incubation assay requiring 25 µL of 1:50 dilution plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary).
• This kit may be used for the analysis of all or any combination of the cancer biomarkers in serum, plasma or tissue/cell lysate and culture. |
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
- Cathepsin D
- Galectin-3
- Ferritin
- Fibroblast Activation Protein
- IGFBP-3
- Melanoma Inhibitory Activation Protein
- Myeloperoxidase
- Sex Hormone Binding Globulin
|
| Assay Panel | Everything you need in a single kit. |
| Cross Reactivity | Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible. |
| Accuracy |
|
| Physicochemical Information
|
| Sensitivity |
- Refer to kit protocol for sensitivities of individual biomarkers.
|
| Standard Curve Range |
- 0.07 - 50 ng/mL: Fibroblast Activation Protein α
- 0.27 - 200 ng/mL: Cathepsin D, IGFBP3
- 0.03 - 25 ng/mL: Ferritin
- 0.004 - 3 ng/mL: Galectin-3
- 0.1 - 75 ng/mL: Melanoma Inhibitory Activity Protein
- 0.02 - 20 ng/mL: Myeloperoxidase
- 0.03 - 25 nM: Sex Hormone Binding Globulin*
*SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard
|
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Storage and Shipping Information
|
| Storage Conditions | Recommended storage for kit components is 2 - 8°C. |
| Packaging Information
|
| Material Size | 96-well plate |
