重要规格表
| Species Reactivity | Key Applications |
|---|---|
| NhP, Fe, Ca | Single Molecule Counting (SMC™) |
| Description | |
|---|---|
| Catalogue Number | 03-0162-00 |
| Trade Name |
|
| Description | SMC™ Human IL-22 High Sensitivity Immunoassay Kit |
| Overview | The SMC™ Human IL-22 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The Erenna® and SMCxPRO™ immunoassay systems detect analytes using Single Molecule Counting (SMC™) technology. |
| Background Information | Interleukin 22 (IL-22), a member of the IL-10 cytokine superfamily, is a potent mediator of cellular inflammatory responses. Mainly produced by natural killer cells and activated T-cells, IL-22 is associated with inflammatory conditions like Crohn’s disease, psoriasis, rheumatoid arthritis, inflammatory bowel disease and ulcerative colitis. |
| Product Information | |
|---|---|
| Components |
|
| Precision, % |
|
| Applications | |
|---|---|
| Application | The sensitivity of the Single Molecule Counting (SMC™) technology gives the SMC™ Human IL-22 High Sensitivity Immunoassay Kit unparalleled performance in the quantification of IL-22 in human serum and plasma. |
| Key Applications |
|
| Application Notes | This new streamline kit has been improved with the following features including new changes and improvements over the legacy IL-22 kit, #03-0059-01: • Applicable for quantifying both serum and plasma samples instead of plasma samples only as in the legacy kit • Improved LLOQ--0.1 pg/mL in the new streamlined kit while the legacy kit is 0.2 pg/mL • Samples now diluted 1:4 rather than neat • Adjusted standard curve--reduced from 100 to 50 pg/mL at the high end • Improved options for sample prep and incubation • Lyophilization of the standard provides the kit at one storage condition • Removal of a plate transfer step • Increased reagent volumes to accommodate automation • Validated to run on both SMCxPRO™ and Erenna® |
| Biological Information | |
|---|---|
| Species Reactivity |
|
| Species Reactivity Note | Although IL-22 was detectable in non-human primate, feline, and canine samples, the assay has not been validated for these species. |
| Accuracy |
|
| Physicochemical Information | |
|---|---|
| Sensitivity |
|
| Product Usage Statements | |
|---|---|
| Usage Statement |
|
| Packaging Information | |
|---|---|
| Material Size | 96 well assay |