millipore,
密理博,HCMBMAG-22K,MILLIPLEX MAP Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay
重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
|---|
| DKK-1, GDF-15, NSE, OPG, Osteonectin (SPARC), Periostin, TRAP5, TWEAK, YKL40
| H
| Mplex
| Luminex xMAP
|
| Description
|
| Catalogue Number | HCMBMAG-22K |
| Trade Name |
|
| Description | MILLIPLEX MAP Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay |
| Overview | The MILLIPLEX MAP Human Cancer/Metastasis Biomarker Panel 1 contains nine metastasis biomarkers that have also been identified in a variety of tumor types. Coupled with the Luminex® xMAP® platform in magnetic bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity. |
| Background Information | Metastasis is a complex process in which tumor cells leave the primary tumor site and migrate to other parts of the body via blood and lymph vessels or by tumor invasion of surrounding tissues and organs. Breaking away from the primary tumor, cancer cells attach to and degrade extracellular matrix proteins that separate tumor from surrounding tissues to escape into the stroma. Where metastases form often depends on the primary tumor. Bone metastases, for example, tend to arise from breast, prostate and kidney tumors. This organ/tissue specificity seems to involve chemical signals from both chemokines and growth factors. |
| Product Information
|
| Detection method | Luminex xMAP |
| Configuration | Design your multiplex kit by choosing available analytes within this panel. |
| Precision, % |
- Intra Assay: < 10%
- Inter Assay: < 16%
|
| Panel Type | MAGNETIC Circulating Cancer |
| Quality Level | MQ200
|
| Applications
|
| Application | Circulating Cancer and Metastasis Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples. |
| Key Applications |
|
| Application Notes | • This is an overnight incubation assay.
• This assay requires 25 μL of 1:10 diluted serum and plasma or tissue/cell culture supernatant |
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
- DKK-1
- GDF-15
- NSE
- OPG
- Osteonectin (SPARC)
- Periostin
- TRAP5
- TWEAK
- YKL40
|
| Assay Panel | Everything you need in a single kit. |
| Cross Reactivity | Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible. |
| Accuracy |
|
| Physicochemical Information
|
| Sensitivity |
- Refer to kit protocol for sensitivities of individual biomarkers.
|
| Standard Curve Range |
- DKK-1: 0.007 – 30 ng/mL
- GDF15: 0.002 – 10 ng/mL
- NSE: 0.036 – 150 ng/mL
- OPG: 0.007 – 30 ng/mL
- Osteonectin (SPARC): 0.976 – 4,00 0ng/mL
- Periostin: 0.195 – 800 ng/mL
- TRAP5: 0,019 – 80 ng/mL
- TWEAK: 0.012 – 50 ng/mL
- YKL40: 0,048 - 20 ng/mL
|
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Storage and Shipping Information
|
| Storage Conditions | Recommended storage for kit components is 2 - 8°C. |
| Packaging Information
|
| Material Size | 96-well plate |
