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密理博,512731,Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem
重要规格表
| Empirical Formula | CAS # |
|---|
| C₂₃H₄₅N₅O₁₄ · H₂SO₄
| 1263-89-4
|
| Description
|
| Overview | An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties. |
| Potency: ≥675 µg/mg. |
| Catalogue Number | 512731 |
| Brand Family |
Calbiochem®
|
| Synonyms | Neomycin E |
| References
|
| References | VanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333. |
| Product Information
|
| CAS number | 1263-89-4 |
| Form | Off-white solid |
| Hill Formula | C₂₃H₄₅N₅O₁₄ · H₂SO₄ |
| Chemical formula | C₂₃H₄₅N₅O₁₄ · H₂SO₄ |
| Structure formula Image |  |
| Quality Level | MQ100
|
| Physicochemical Information
|
| Toxicological Information
|
| Safety Information according to GHS
|
| RTECS | WK2320000 |
| Safety Information
|
| R Phrase | R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed. |
| S Phrase | S: 22-24/25-36/37/39-45
Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Harmful
|
| Storage |
+15°C to +30°C
|
| Do not freeze |
Ok to freeze
|
