| Description | |
|---|---|
| Overview | A novel quaternary pyridinium poly-amino acid present in elastin. Suggested to be responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. |
| Catalogue Number | 263275 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Akagawa, M., and Suyama, K. 2000. Connect. Tissue Res. 41, 131. Bode, D.C., et al. 2000. Pulm. Pharmacol. Therap. 13, 175. Viglio, S., et al. 2000. Eur. Respir. J. 15, 1039. Davis, N.R., and Anwar, R.A. 1970. J. Am. Chem. Soc. 92, 3778. Thomas, J., et al. 1963. Nature 200, 651. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Lyophilized |
| Hill Formula | C₂₄H₃₉N₅O₈ |
| Chemical formula | C₂₄H₃₉N₅O₈ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image |  |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Cross-linking of elastin |
| Purity | ≥99% by TLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Standard Handling |
| Storage | -20°C |
| Protect from Light | Protect from light |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
