millipore,密理博,203408,BLEOCIN Antibiotic, Streptomyces verticillus, Cell Culture-Tested - CAS 55658-47-4 - Calbiochem
重要规格表
| Empirical Formula | CAS # |
|---|---|
| C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl | 55658-47-4 |
| Description | |
|---|---|
| Overview | A unique antibiotic of the bleomycin family that is toxic to eukaryotic and prokaryotic cells. BLEOCIN™ Antibiotic cleaves double-stranded DNA and inhibits DNA synthesis, resulting in cell death. Can be used for selection of recombinant clones in a variety of cell types transfected with vectors containing a ble resistance marker. Copper content: ≥3.5%. Potency: ≥750 µg/mg. |
| Catalogue Number | 203408 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Sergeev, D.S., et al. 1995. Bioorg. Khim. 21, 695. Mulsant, P., et al. 1988. Somatic Cell and Molecular Genetics 14, 243. Ehrenfeld, G.M., et al. 1987. Biochemistry 26, 931. Takita, T., et al. 1972. J. Antibiot. 25, 755. |
| Product Information | |
|---|---|
| CAS number | 55658-47-4 |
| Form | Blue lyophilized solid |
| Hill Formula | C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl |
| Chemical formula | C₅₇H₈₉CuN₁₉O₂₁S₂ · 3HCl |
| Hygroscopic | Hygroscopic |
| Structure formula Image |  |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | ≥85% by HPLC |
| Safety Information according to GHS | |
|---|---|
| RTECS | EC5990700 |
| Safety Information | |
|---|---|
| R Phrase | R: 20/21/22-36/37/38-40-42/43 Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact. |
| S Phrase | S: 22-26-36/37/39-45 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Harmful & Carcinogenic / Teratogenic |
| Storage | +2°C to +8°C |
| Protect from Light | Protect from light |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C. |
