重要规格表
| Empirical Formula | CAS # |
|---|
| C₄H₁₀O₂S₃
| 145626-87-5
|
| Description
|
| Overview | Water-soluble reagent useful for the reduction of native disulfide bonds in proteins. Considered to be a superior reducing agent to DTT. Shown to reduce accessible disulfide bonds in immunoglobulin and trypsinogen under non-denaturing conditions 5 to 7 times faster than DTT at pH 7. The relatively less accessible disulfide bond in α-chymotrypsinogen A was reduced 2.3 times faster at with BMS than with DTT at pH 7.0. |
| Catalogue Number | 203325 |
| Brand Family |
Calbiochem®
|
| Synonyms | bis(2-Mercaptoethylsulfone) |
| References
|
| References | Singh, R., et al. 1995. Methods Enzymol. 251, 167.
Singh, R., and Whitesides, G.M. 1994. Bioorg. Chem. 22, 109.
Singh, R., and Whitesides, G.M. 1994. Protein Sci. 3, Suppl. 1, 430T.
Lamoureux, G.V., and Whitesides, G.M. 1993. J. Org. Chem. 58, 633. |
| Product Information
|
| CAS number | 145626-87-5 |
| Form | White crystalline solid |
| Hill Formula | C₄H₁₀O₂S₃ |
| Chemical formula | C₄H₁₀O₂S₃ |
| PKA | 7.9 and 9.0 |
| Structure formula Image |  |
| Quality Level | MQ100
|
| Biological Information
|
| Purity | ≥99% by titration |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Standard Handling
|
| Storage |
-20°C
|
| Do not freeze |
Ok to freeze
|
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. |
| Packaging Information
|
| Packaged under inert gas |
Packaged under inert gas
|
