millipore,
密理博,03-0112-00,SMC Interleukin 23 (IL-23) IMMUNOASSAY KIT
重要规格表
| Analytes Available | Species Reactivity | Key Applications |
|---|
| IL-23
| H
| Single Molecule Counting (SMC™)
|
| Description
|
| Catalogue Number | 03-0112-00 |
| Trade Name |
|
| Description | SMC™ Interleukin 23 (IL-23)
IMMUNOASSAY KIT |
| Overview | The SMC™ IL-23 Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology. |
| Background Information | Interleukin-23 (IL-23) is an endogenous cytokine responsible for the production of IL-17 from memory T-lymphocytes. The active human form of IL-23 is heterodimeric, consisting of a p40 subunit shared with IL-12, and a p19 subunit unique to IL-23. The p19 subunit is expressed by T-lymphocytes, activated macrophages, dendritic and endothelial cells. IL-23 also promotes upregulation of MMP-9 and the stimulation of helper T-lymphocytes to Th17 cells. The proinflammatory characteristics of IL-23 make it a target of interest for a number of Th17 autoimmune disorders, including Crohn’s disease, colitis, inflammatory bowel disease, and psoriasis. |
| Product Information
|
| Components |
- Assay Buffer
- Human IL-23 Coated Beads
- Standard Diluent
- Human IL-23 Detection Antibody
- Human IL-23 Standard
- SMC™ Human IL-23 Immunoassay Kit Instructions
- 10X Wash Buffer
- Elution Buffer B
- Buffer D
|
| Precision, % |
- Low-end CV% Range: 0-13%
- Low-end CV% Average: 6%
|
| Quality Level | MQ200
|
| Applications
|
| Application | The sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Human IL-23 Immunoassay Kit unparalleled performance in the quantification of IL-23 in human EDTA plasma and serum. |
| Key Applications |
- Single Molecule Counting (SMC™)
|
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
|
| Accuracy |
- Minimum of 10 samples spiked with acceptable recovery between 80-120%.
|
| Physicochemical Information
|
| Linearity of Dilution | Minimum of 10 samples spiked and diluted (at least 3 dilutions) with acceptable recovery between 80-120%. |
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Packaging Information
|
| Material Size | 96 well assay |
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