millipore,
密理博,03-0123-00,SMC Mouse IL-17A Discovery Immunoassay Kit
重要规格表
| Analytes Available | Species Reactivity | Key Applications |
|---|
| IL-17A
| M
| Single Molecule Counting (SMC™)
|
| Description
|
| Catalogue Number | 03-0123-00 |
| Trade Name |
|
| Description | SMC™ Mouse IL-17A Discovery Immunoassay Kit |
| Overview | The SMC™ Mouse IL-17A Discovery Immunoassay Kit contains all reagents required to perform the assays. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology. |
| Background Information | Interleukin-17A (IL-17A) is the founding member of a group of cytokines called the IL-17 family. There are several members of the IL-17 family, from IL-17A to IL-17F (IL-17E is also called IL-25). IL-17A is involved in mediating proinflammatory responses by inducing the production of many other cytokines, chemokines, and prostaglandins from many cell types. The increased expression of chemokines attracts other cells, including neutrophils. IL-17A has many physiological functions, such as airway remodeling. As a result of these roles, the IL-17 family has been linked to many immune/autoimmune related diseases, including rheumatoid arthritis (RA), asthma, allergic responses, lupus, allograft rejection and antitumor immunity. |
| Product Information
|
| Components |
- Assay Plate
- 10X PBS
- Blocking Buffer
- Standard Diluent
- Mouse IL-17A Detection Antibody
- Mouse IL-17A Standard
- SMC™ Mouse IL-17A Immunoassay Kit Instructions
- 10X Wash Buffer
- Buffer C
- Elution Buffer B
|
| Precision, % |
- Low-end CV% Range: 0-20%
- Low-end CV% Average: 11%
|
| Quality Level | MQ200
|
| Applications
|
| Application | The Single Molecule Counting (SMC™) technology gives the SMC™ Mouse IL-17A Discovery Immunoassay Kit unparalleled performance in the quantification of IL-17A in mouse serum. |
| Key Applications |
- Single Molecule Counting (SMC™)
|
| Biological Information
|
| Species Reactivity |
|
| Analytes Available |
|
| Accuracy |
- Minimum of 10 samples spiked with acceptable recovery between 80-120%.
|
| Physicochemical Information
|
| Linearity of Dilution | Minimum of 10 samples spiked and diluted (at least 3 dilutions) with acceptable recovery between 80-120%. |
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Packaging Information
|
| Material Size | 96 well assay |
