millipore,
密理博,HCVD6MAG-67K,MILLIPLEX MAP Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay
重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
|---|
| sCD14, sCD26, Endostatin, pGRN, LRG1, MCAM/sCD146, ucMGP
| H
| Mplex
| Luminex xMAP
|
| Description
|
| Catalogue Number | HCVD6MAG-67K |
| Trade Name |
|
| Description | MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay |
| Overview | The MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 6 may be used to simultaneously quantify any or all the the following: Soluble Cluster of Differentiation 14 (sCD14); Dipeptidyl Peptidase-4 (DPP4/DPPIV) / Soluble Cluster of Differentiation 26 (sCD26); Endostatin / Collagen Alpha-1 (XVIII) (COL181A); Progranulin (pGRN) / Proepithelin (PEPI) / PC Cell-derived Growth Factor (PCDGF) / Acrogranin / Paragranulin; Leucine-rich Alpha-2-Glycoprotein 1 (LRG1); Melanoma Cell Adhesion Molecule (MCAM) / Soluble Cluster of Differentiation 146 (sCD146) / Cell Surface Glycoprotein MUC18; Uncarboxylated Matrix Gamma-Carboxyglutamate (Gla) Protein (ucMGP) |
| Background Information | Cardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases. |
| Product Information
|
| Detection method | Luminex xMAP |
| Configuration | Design your multiplex kit by choosing available analytes within this panel. |
| Precision, % |
- sCD14: Intra-assay <5% CV; Inter-assay <20%
- DPP4/sCD26: Intra-assay <5% CV; Inter-assay <10% CV
- Endostatin: Intra-assay <5% CV; Inter-assay <10% CV
- pGRN: Intra-assay <5% CV; Inter-assay <10% CV
- LRG1: Intra-assay <5% CV; Inter-assay <10% CV
- MCAM: Intra-assay <5% CV; Inter-assay <10% CV
- ucMGP: Intra-assay <10% CV; Inter-assay <20% CV
|
| Panel Type | MAGNETIC Cardiovascular |
| Quality Level | MQ200
|
| Applications
|
| Application | The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP |
| Key Applications |
|
| Application Notes | For optimal sensitivity, use an overnight (16-18 hour) incubation. A two hour incubation can also be used (though sensitivity may be lower). Serum and plasma samples require (recommend) a 1:500 dilution with Assay Buffer. Tissue culture supernatants may be run neat or appropriately diluted in control medium. Each well requires 25 μL of sample, standard or control. |
| Biological Information
|
| Specificity | Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible. |
| Species Reactivity |
|
| Analytes Available |
- sCD14
- sCD26
- Endostatin
- pGRN
- LRG1
- MCAM/sCD146
- ucMGP
|
| Assay Panel | Everything you need in a single kit. |
| Cross Reactivity | There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel. |
| Accuracy |
- sCD14 102%
- DPP4/sCD26 97%
- Endostatin 92%
- pGRN 103%
- LRG1 103%
- MCAM 86%
- ucMGP 95%
|
| Physicochemical Information
|
| Sensitivity |
- MinDC+2SD
- sCD14: 0.016 ng/mL
- DPP4: 0.041 ng/mL
- Endostatin: 0.007 ng/mL
- pGRN: 0.014 ng/mL
- LRG1: 0.015 ng/mL
- MCAM: 0.016 ng/mL
- ucMGP: 0.052 ng/mL
|
| Linearity of Dilution | Contact technical support for this information |
| Standard Curve Range |
- sCD14: 0.01 - 40 ng/mL
- DPP4/sCD26: 0.049 - 200 ng/mL
- Endostatin: 0.002 - 10 ng/mL
- pGRN: 0.024 - 100 ng/mL
- LRG1: 0.024 -100 ng/mL
- MCAM: 0.024 - 100 ng/mL
- ucMGP: 0.049 - 200 ng/mL
|
| Product Usage Statements
|
| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
|
| Storage and Shipping Information
|
| Storage Conditions | Recommended storage for kit components is 2 - 8°C. |
| Packaging Information
|
| Material Size | 96-well plate |
