millipore,
密理博,220201,CHAPS, Molecular Biology Grade - CAS 75621-03-3 - Calbiochem
重要规格表
| Empirical Formula | CAS # |
|---|
| C₃₂H₅₈N₂O₇S
| 75621-03-3
|
| Description
|
| Overview | Zwitterionic detergent that combines features of bile salts and N-alkyl sulfobetaines. Better at solubilizing proteins than structurally-related carboxylic acid anions and is much more effective at breaking protein-protein interactions than either sodium cholate or TRITON® X-100 Detergent. Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Also, capable of disaggregating cytochrome P450 to its monomeric form without denaturation. Has a small micellar molecular weight and a high critical micellar concentration and can be removed from either gels or protein solutions by dialysis across a membrane. Aggregation number: 4-14. |
| Conductivity (1.0 M, 24°C): <100 µmhos. |
| Catalogue Number | 220201 |
| Brand Family |
Calbiochem®
|
| Synonyms | 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate |
| References
|
| References | Chen, Y., et al. 1992. Biochemistry 31, 2415.
Ofri, D., et al. 1992. J. Neurochem. 58, 628.
Ransom, R.W., et al. 1992. Biochem. Pharmacol. 43, 1823.
Simonds, W.F., et al. 1992. Proc. Natl. Acad. Sci. USA 77, 4623.
Yannariello-Brown, J., and Weigel, P.H. 1992. Biochemistry 31, 576.
Hjelmeland, L.M. 1980. Proc. Natl. Acad. Sci. USA 77, 6368.
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 4623. |
| Product Information
|
| CAS number | 75621-03-3 |
| Aggregation Number | 4 - 14 |
| CMC | 6 - 10 mM |
| Form | White crystalline powder |
| Hill Formula | C₃₂H₅₈N₂O₇S |
| Chemical formula | C₃₂H₅₈N₂O₇S |
| Hygroscopic |
Hygroscopic
|
| Micellar weight | 6150 |
| Quality Level | MQ100
|
| Biological Information
|
| Purity | ≥98% by NMR |
| Physicochemical Information
|
| Contaminants | DNase, RNase, and Protease: none detected |
| Toxicological Information
|
| Safety Information according to GHS
|
| Safety Information
|
| R Phrase | R: 22-36/38
Harmful if swallowed.
Irritating to eyes and skin. |
| S Phrase | S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing. |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Harmful
|
| Storage |
+15°C to +30°C
|
| Hygroscopic |
Hygroscopic
|
| Do not freeze |
Ok to freeze
|
| Special Instructions | Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C. |
