millipore,密理博,196419,BAPTA/AM - CAS 126150-97-8

millipore,密理博,196419,BAPTA/AM - CAS 126150-97-8 - Calbiochem

重要规格表

Empirical Formula	CAS #
C₃₄H₄₀N₂O₁₈	126150-97-8

Description
Overview	Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D₃-induced increase in intracellular Ca²⁺. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.
Catalogue Number	196419
Brand Family	Calbiochem®
Synonyms	1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester

References
References	Bissonnette, M., et al. 1994. Am. J. Physiol. 267, G465. Jiang, S., et al. 1994. Exp. Cell Res. 212, 84. Billman, G.E. 1993. Am. J. Physiol. 265, H1529. Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171. Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133. Harrison, S.M., and Bers, D.M. 1987. J. Biophys. 51, 102A. Marban, E., et al. 1986. J. Clin. Invest. 78, 1185. Tsien, R.Y. 1981. Nature 290, 527. Tsien, R.Y. 1980. Biochemistry 19, 2396.

References

Bissonnette, M., et al. 1994. Am. J. Physiol. 267, G465.
Jiang, S., et al. 1994. Exp. Cell Res. 212, 84.
Billman, G.E. 1993. Am. J. Physiol. 265, H1529.
Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171.
Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133.
Harrison, S.M., and Bers, D.M. 1987. J. Biophys. 51, 102A.
Marban, E., et al. 1986. J. Clin. Invest. 78, 1185.
Tsien, R.Y. 1981. Nature 290, 527.
Tsien, R.Y. 1980. Biochemistry 19, 2396.

Product Information
CAS number	126150-97-8
Form	Light yellow solid
Hill Formula	C₃₄H₄₀N₂O₁₈
Chemical formula	C₃₄H₄₀N₂O₁₈
Structure formula Image
Quality Level	MQ100

Biological Information
Purity	≥90% by TLC

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot, purge with inert gas and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.