重要规格表
| Empirical Formula | CAS # |
|---|
| C₂₂H₂₀N₂O₁₀ · 4Na
| 126824-24-6
|
| Description
|
| Overview | Ca2+ chelator exhibiting a 105-fold greater affinity for Ca2+ (Kd = 110 nM) than for Mg2+. After BAPTA complexes with Ca2+, the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca2+ levels, especially transient phenomena, because of its insensitivity to pH. Useful for the measurement and control of Ca2+ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+. Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy. |
| Catalogue Number | 196418 |
| Brand Family |
Calbiochem®
|
| Synonyms | 1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid, 4Na |
| References
|
| References | DeLorenzo, R.J., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14482.
Li, L., et al. 1995. J. Cell Physiol. 163, 105.
Tymianski, M., et al. 1994. J. Neurophysiol. 72, 1973. |
| Product Information
|
| CAS number | 126824-24-6 |
| Form | White to off-white solid |
| Hill Formula | C₂₂H₂₀N₂O₁₀ · 4Na |
| Chemical formula | C₂₂H₂₀N₂O₁₀ · 4Na |
| Hygroscopic |
Hygroscopic
|
| Structure formula Image |  |
| Quality Level | MQ100
|
| Safety Information
|
| R Phrase | R: 36/37/38
Irritating to eyes, respiratory system and skin. |
| S Phrase | S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing. |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Irritant
|
| Storage |
-20°C
|
| Protect from Light |
Protect from light
|
| Hygroscopic |
Hygroscopic
|
| Do not freeze |
Ok to freeze
|
| Special Instructions | Following reconstitution, aliquot, purge with inert gas and freeze (-20°C). To increase stability in solution, store at a high pH (>10). Stock solutions are stable for up to 1 month at -20°C. |
