| 描述 | |
|---|---|
| 产品目录编号 | MAIPN4550 |
| 商名 |
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| 描述 | MultiScreen-IP，0.45 µm，无色，非无菌 |
| 背景信息 | Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates. MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport. Membranes have uniform pore structure and density for reliable transport: - Individual wells minimize candidate cross-talk - Compatibility with automated liquid handling systems increases throughput Permeability Assay: - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1 PAMPA Assay: - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3 MultiScreen Acceptor Plate: - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated. |
| 产品信息 | |
|---|---|
| 自动化兼容性 | No |
| 过滤器代码 | IP |
| 色码 | 透明 |
| 孔数 | 96 |
| Quality Level | MQ400 |
| 应用 | |
|---|---|
| 应用 | 亲合素/生物素连锁，DNA-结合蛋白，蛋白质结合，PAMPA |
| 主要应用 |
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| 生物信息 | |
|---|---|
| 媒质 | Immobilon®-P |
| 无菌性 | 非无菌 |
| 理化信息 | |
|---|---|
| 孔径 | 0.45 µm |
| 尺寸 | |
|---|---|
| 过滤面积 | 0.3cm2 |
| 体积 | 50 µL–250 µL |
| 材料信息 | |
|---|---|
| 化学 |
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| 装置材料 |
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| 包装信息 | |
|---|---|
| 数量 | 50 |
