millipore,
密理博,HANG2MAG-12K,MILLIPLEX MAP Human Angiogenesis Panel 2, HANG2MAG-12K
| Description
|
| Catalogue Number | HANG2MAG-12K |
| Trade Name |
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| Description | MILLIPLEX® MAP Human Angiogenesis Panel 2, HANG2MAG-12K |
| Overview | MILLIPLEX® MAP Human Angiogenesis Magnetic Bead Panel 2 contains all the components necessary to measure up to 20 biomarkers in any combination using Luminex® xMAP® technology. This kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls, and can measure up to 38 serum, plasma or cell/tissuue culture samples in duplicate. |
| Background Information | Angiogenesis, the development of new vascular networks, is a key process in normal growth and development as well as in wound healing, with homeostasis maintained by a delicate balance of angiogenic factors and inhibitors. Consequently, insufficient or excessive blood vessel growth underlies many diseases, including cardiovascular disease, diabetic ulcers, macular degeneration and cancer. Angiogenesis plays a significant role in tumor growth and metastasis. |
| Product Information
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| Detection method | Luminex xMAP |
| Configuration | Design your multiplex kit by choosing available analytes within this panel. |
| Precision, % |
- Inter-assay: < XX
- Intra-Assay: < XX
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| Panel Type | MAGNETIC Circulating Cancer |
| Quality Level | MQ200
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| Applications
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| Application | Angiogenesis Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples. |
| Key Applications |
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| Application Notes | • This is an overnight assay requiring 25 µL of 1:5 diluted plasma or serum samples, or 25 µL cell culture supernatant per well.
• This kit may be used for the analysis of all or any combination of the Human Angiogenesis Panel 2 analytes in tissue/cell lysate and culture supernatant or in serum and plasma. |
| Biological Information
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| Specificity | Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible. |
| Species Reactivity |
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| Analytes Available |
- Angiostatin
- AXL (soluble)/sAXL
- c-Kit (soluble) / sc-Kit / sSCFR
- E-Selectin (soluble) / sE-Selectin
- EGFR (soluble) / sEGFR / sErbB1 / sHER1
- HER2 (soluble) / sHER2 / sErbB2
- HER3 (soluble) / sHER3 / sErbB3
- HGFR (soluble) / sHGFR / sc-Met
- Tenascin C / TN-C
- Thrombospondin-2 / TSP-2
- IL-6Rα (soluble) / sIL-6Rα
- Neuropilin-1 (soluble) / sNRP-1
- TIE-2 (soluble) / sTIE-2
- uPAR (soluble) / suPAR
- VEGFR1 (soluble) / sVEGFR1 / sFlt-1
- VEGFR2 (soluble) / sVEGFR2 / sKDR / sFlk-1
- VEGFR3 (soluble) / sVEGFR3 / sFlt-4
- Osteopontin (OPN)
- PDGF-AB/BB
- PECAM-1 (soluble) / sPECAM-1 / sCD31
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| Assay Panel | Everything you need in a single kit. |
| Cross Reactivity | Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible. |
| Accuracy |
|
| Physicochemical Information
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| Sensitivity |
- See kit protocol for individual analytes sensitivities.
|
| Linearity of Dilution | Contact technical support for this information |
| Standard Curve Range |
- Angiostatin: 274 – 200,000 pg/mL
- sAXL: 14 – 10,000 pg/mL
- sc-Kit/sSCFR: 41 – 30,000 pg/mL
- sE-Selectin: 274 – 200,000 pg/mL
- sEGFR: 41 – 30,000 pg/mL
- sHER2: 41 – 30,000 pg/mL
- sHER3: 14 – 10,000 pg/mL
- sHGFR: 69 – 50,000 pg/mL
- sIL-6Rα: 27 – 20,000 pg/mL
- sNeuropilin-1: 274 – 200,000 pg/mL
- Osteopontin (OPN): 41 – 30,000 pg/mL
- PDGF-AB/BB: 7 – 5,000 pg/mL
- sPECAM-1: 27 – 20,000 pg/mL
- Tenascin C: 27 – 20,000 pg/mL
- Thrombospondin-2: 137 – 100,000 pg/mL
- sTIE-2: 27 – 20,000 pg/mL
- suPAR: 137 – 100,000 pg/mL
- sVEGFR1: 14 – 10,000 pg/mL
- sVEGFR2: 137 – 100,000 pg/mL
- sVEGFR3: 412 – 300,000 pg/mL
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| Toxicological Information
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| Safety Information according to GHS
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| Product Usage Statements
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| Usage Statement |
- Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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| Storage and Shipping Information
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| Storage Conditions | Recommended storage for kit components is 2 - 8°C. |
| Packaging Information
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| Material Size | 96-well plate |
