重要规格表
| Empirical Formula | CAS # |
|---|---|
| C₂₀H₂₈O₂ | 302-79-4 |
| Description | |
|---|---|
| Overview | Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells. PROTECT FROM AIR. |
| Catalogue Number | 554720 |
| Brand Family | Calbiochem® |
| Synonyms | Tretinoin, ATRA, Vitamin A Acid |
| References | |
|---|---|
| References | Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503. Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684. Labbaye, C., et al. 1993. Blood 81, 475. Sakashita, A., et al. 1993. Blood 81, 1009. Situ, R., et al. 1993. Dermatology 186, 38. Tini, M., et al. 1993. Genes Develop. 7, 295. Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427. Sharpe, C.R. 1991. Neuron 7, 239. Thaller, C. and Eichele, G. 1990. Nature 345, 815. |
| Product Information | |
|---|---|
| CAS number | 302-79-4 |
| Form | Yellow solid |
| Hill Formula | C₂₀H₂₈O₂ |
| Chemical formula | C₂₀H₂₈O₂ |
| Hygroscopic | Hygroscopic |
| Structure formula Image |  |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | ≥95% by assay |
| Safety Information according to GHS | |
|---|---|
| RTECS | VH6475000 |
| Safety Information | |
|---|---|
| R Phrase | R: 22-36/37/38-63 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child. |
| S Phrase | S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Harmful & Carcinogenic / Teratogenic |
| Storage | +2°C to +8°C |
| Protect from Light | Protect from light |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C. |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
