重要规格表
| Empirical Formula |
|---|
| C₁₃₁H₂₂₄N₃₂O₃₇ |
| Description | |
|---|---|
| Overview | A water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM; micelle MW ~ 23,100; aggregation number ~ 8.1; partial specific volume ~ 0.77 cm3/g). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins. |
| Catalogue Number | 437600 |
| Brand Family | Calbiochem® |
| Synonyms | Lipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂ |
| References | |
|---|---|
| References | McGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171. |
| Product Information | |
|---|---|
| CMC | < 1 μM |
| Form | White lyophilized |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₁₃₁H₂₂₄N₃₂O₃₇ |
| Chemical formula | C₁₃₁H₂₂₄N₃₂O₃₇ |
| Hygroscopic | Hygroscopic |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Peptide Sequence | Ac-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂ |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Irritant |
| Storage | +2°C to +8°C |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
