重要规格表
| Empirical Formula | CAS # |
|---|---|
| C₅H₉N₃ | 51-45-6 |
| Description | |
|---|---|
| Overview | A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H1 receptors leads to Ca2+ mobilization, whereas histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells. |
| Catalogue Number | 3779 |
| Brand Family | Calbiochem® |
| Synonyms | 2-(4-Imidazolyl)ethylamine |
| References | |
|---|---|
| References | Robinson, A.J., and Dickerson, J.M. 2001. Br. J. Pharmacol. 133, 178. Izumi, H., et al. 1995. Am. J. Obstet. Gynecol. 172, 1477. Vannier, E., and Dinarello, C.A. 1994. J. Biol. Chem. 269, 9952. Yan, Q.Z., et al. 1994. Agents Actions 41, C111. Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109. Bloom, F.E. 1990. in Pharmacological Basis of Therapeutics p. 224 (Gilman, A.G., et al., Eds.) Pergamon Press, New York. |
| Product Information | |
|---|---|
| CAS number | 51-45-6 |
| Form | White solid |
| Hill Formula | C₅H₉N₃ |
| Chemical formula | C₅H₉N₃ |
| Hygroscopic | Hygroscopic |
| Structure formula Image |  |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | ≥97% by TLC |
| Safety Information according to GHS | |
|---|---|
| RTECS | MS1050000 |
| Safety Information | |
|---|---|
| R Phrase | R: 22-36/37/38-42/43 Harmful if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by inhalation and skin contact. |
| S Phrase | S: 26-36/37-22 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves. Do not breathe dust. |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Harmful |
| Storage | +2°C to +8°C |
| Protect from Light | Protect from light |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
