重要规格表
| Empirical Formula | CAS # |
|---|---|
| C₂₅H₄₈N₆O₈·CH₄O₃S | 138-14-7 |
| Description | |
|---|---|
| Overview | Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Completely protects against dopamine-induced cell death. Has also been shown to interfere with hydroxyl radical formation, which mediates tissue damage in several disease states. Shows anti-proliferative effect on vascular smooth muscle cells in vitro and in vivo. Can also inhibit the oxidative chemistry of peroxynitrite by reaction of the hydroxamic acid moieties with trans-peroxynitrous acid. |
| Catalogue Number | 252750 |
| Brand Family | Calbiochem® |
| Synonyms | Desferrioxamine Mesylate, DFOM, Iron Chelator II |
| References | |
|---|---|
| References | Bergeron, R.J., et al. 1996. J. Med. Chem. 39, 1575. Ben-Shachar, D., et al. 1995. J. Neurochem. 64, 718. Denicola, A., et al. 1995. Free Radic. Biol. Med. 19, 11. Dzwigaj, S., and pererat, H., 1995. Free Radic. Res. 14, 103. Dang, S., et al. 1994. Res. Commun. Mol. Pathol. Pharmacol. 86, 43. Porreca, E., et al. 1994. Arterioscler. Thromb. 14, 299. |
| Product Information | |
|---|---|
| CAS number | 138-14-7 |
| Form | Faint yellow powder |
| Hill Formula | C₂₅H₄₈N₆O₈·CH₄O₃S |
| Chemical formula | C₂₅H₄₈N₆O₈·CH₄O₃S |
| Hygroscopic | Hygroscopic |
| Structure formula Image |  |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | 92.5-100% by TLC |
| Safety Information according to GHS | |
|---|---|
| RTECS | UG5310000 |
| Safety Information | |
|---|---|
| R Phrase | R: 22-36/37/38-40-42/43 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact. |
| S Phrase | S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Harmful & Carcinogenic / Teratogenic |
| Storage | +2°C to +8°C |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Special Instructions | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
