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密理博,233155,Cleland’s Reagent - CAS 3483-12-3 - Calbiochem
重要规格表
| Empirical Formula | CAS # |
| C₄H₁₀O₂S₂
| 3483-12-3
|
| Description
|
| Overview | A protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations. |
| Oxidized dithiothreitol: ≤0.5%. |
| Catalogue Number | 233155 |
| Brand Family |
Calbiochem®
|
| Synonyms | DTT, Dithiothreitol |
| References
|
| References | Gailis, L. 1994. Eur. J. Pharmacol. 292, 39. Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125. Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199. Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716. Cleland, W.W. 1964. Biochemistry 3, 480. |
| Product Information
|
| CAS number | 3483-12-3 |
| Form | White to off-white powder |
| Hill Formula | C₄H₁₀O₂S₂ |
| Chemical formula | C₄H₁₀O₂S₂ |
| Quality Level | MQ100
|
| Biological Information
|
| Purity | ≥97% by titration |
| Physicochemical Information
|
| Contaminants | Heavy metals: ≤1 ppm |
| Heavy metals | <1 ppm |
| Safety Information according to GHS
|
| RTECS | EK1610000 |
| Safety Information
|
| R Phrase | R: 22-36/38
Harmful if swallowed. Irritating to eyes and skin. |
| S Phrase | S: 36-26
Wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Harmful
|
| Storage |
+2°C to +8°C
|
| Do not freeze |
Ok to freeze
|
| Special Instructions | Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
| Packaging Information
|
| Packaged under inert gas |
Packaged under inert gas
|