millipore,
密理博,116833,Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem
重要规格表
| Empirical Formula |
| C₁₇H₁₆ClN₅O₆PS • Na
|
| Description
|
| Overview | A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. |
| Note: 5 µmol = 2.54 mg. |
| Catalogue Number | 116833 |
| Brand Family |
Calbiochem®
|
| Synonyms | 8-CPT-2ʹ-O-Me-cAMP, Na |
| References
|
| References | Kang, G., et al. 2003. J. Biol. Chem. 278, 8279. Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901. |
| Product Information
|
| Declaration | Sold under license of European Patent Application 02/077,219.0. |
| Form | Lyophilized |
| Hill Formula | C₁₇H₁₆ClN₅O₆PS • Na |
| Chemical formula | C₁₇H₁₆ClN₅O₆PS • Na |
| Hygroscopic |
Hygroscopic
|
| Structure formula Image |  |
| Quality Level | MQ100
|
| Biological Information
|
| Purity | ≥98% by HPLC |
| Storage and Shipping Information
|
| Ship Code |
Ambient Temperature Only
|
| Toxicity |
Standard Handling
|
| Storage |
-20°C
|
| Hygroscopic |
Hygroscopic
|
| Do not freeze |
Ok to freeze
|
| Special Instructions | Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |